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Unbound's first all-natural muscle building/hardening supplement, containing patented versions of the commonly used ingredients, Laxogenin, Epicatechin, and Phosphatidic Acid.
Phosphatidic Acid is a unique type of fat molecule that directly activates mTOR -- the signaling pathway that drives muscle protein synthesis in humans. Research indicates that phosphatidic acid supplementation enhances the anabolic (muscle building) effects of resistance-training programs. In fact, studies show that resistance-trained athletes consuming 750mg of phosphatidic acid (the same dose included in BYLD) daily for 8 weeks, in conjunction with a strenuous resistance-training program yielded significant benefits in size and strength compared to placebo. *
Epicatechin is a bioactive flavanol found in trace amounts in many foods, including dark chocolate and green tea, that is widely regarded for its myostatin-inhibiting properties. Myostatin is a protein that is found in skeletal muscle that stunts muscle growth. Epicatechin is also known to stimulate mitochondrial biogenesis and nitric oxide (NO) production, encouraging greater blood flow and nutrient delivery. *
Apigenin is a bioflavonoid found in a number of plants, including chamomile, onions, grapefruits, and celery, that has the unique ability to inhibit 17β-hydroxysteroid dehydrogenase (17β-HSD). Animal studies also indicate that apigenin supports muscle protein synthesis (and therefore hypertrophy) via increased phosphorylation of several key players in the mTOR pathway, including Akt, S6K1, and 4E-BP1. *
AstraGin is a novel complex of highly purified and fractionated Panax notoginseng and Astragalus membranaceus shown in 16 in-vitro and eight in-vivo studies to increase bioavailability and absorption of several key nutrients, including the uptake of numerous amino acids (e.g. leucine 58% increase). AstraGin may also support better muscle recovery and growth following training as studies on ginsenosides (one of the active components in AstraGin) note that it activates the mTOR signal pathway by regulating upstream kinases in muscle cells.