* Percent daily values are based on a 2000 calorie diet

† Daily Value not established

UC•II® Joint Regeneration Agent – Undenatured Type-II Collagen  (40 mg)
A powerful joint-specific anti-inflammatory and a newly discovered antioxidant that helps address oxidative damage to joints. UC•II has been found to be superior, safe, completely natural and effective ingredient for joint and pain management. This superior ingredient is effective at pain and joint management and is manufactured through a low-temperature process that ensures the biological activity remains intact.

Best of all, the type of collagen most abundant in joints is the same collagen in ALLFLEX with UC•II®. Over 30 years of double-blind, placebo controlled studies indicate that it actually helps in the synthesis of new cartilage in challenged joints. (Protected by 4 separate US Patents.)

UC•II is a revolutionary new approach to joint and pain management and is backed by six human clinical trials, including one conducted at the prestigious Harvard University that found that study participants experienced substantial improvement with the addition of UC•II® and best of all, experienced no side effects .

In research, Boswellic Extract was found to reduce inflammation by inhibiting proinflammatory 5-lipoxygenase chemicals and blocking leukotriene synthesis. Those with joint pain are often looking for a natural alternative and 3-Lastin provides a well-tolerated and safe alternative.

OptiMSM® Collagen Synthesis Activator – Methylsulfonylmethane (MSM) (450 mg)
MSM helps repair damaged cells and promotes the growth of healthy new cells. MSM is necessary for joint collagen synthesis. Collagen builds a powerful matrix to help strengthen joint tissue, while providing flexibility. It is also a protein and essential for the growth and repair of cells.

MSM is a natural sulphur compound in fruit, vegetables, fish, milk and grains. In Human clinical research trials, MSM was found to relieve pain and stiffness and reduce swelling and inflammation. It has been found to be a safe and effective method to provide joint comfort and increase joint range of motion.

Curcumin Antioxidant Powerhouse – Curcuma Longa (100 mg)
Curcumin provides powerful joint tissue protection from Free Radical Oxidative damage at the cellular level and has been found to be more than more than 300 times the antioxidant power than vitamin E. This has been used in traditional Asian medicine to alleviate pain associated with arthritis and reduce inflammation. Furthermore, it can help inhibit the production of prostaglandins.

Salix Alba – White Willow Extract (100 mg)
The ultra pure, bioavailable herbal extract Salix Alba has been carefully combined with the core ALLFLEX ingredients to reduce inflammation, joint pain, swelling and stiffness.
Salix Alba or white willow extract is derived from a large tree indigenous to Central and Southern Europe, Asia and North America and has long been utilized for its inflammation properties. It has been recorded as being one of the oldest forms of natural painkillers in human history.

Specifically, the inner bark of white willow contains tannins that have been suggested as being responsible for pain relief and reduction. It has also been found to inhibit prostaglandins (chemicals produced in response to injury to the body). White willow often referred to as nature’s aspirin and provides a powerful but completely natural approach to treating aches and pains.

Vitamin C and E complex

Vitamin C – Calcium Ascorbate (40mg or 100% RDI)
Vitamin C is a water-soluble vitamin and antioxidant that is essential for high performance athletes. It provides support to the immune system under stress and intense training, and helps maintain collagen, which is essential for the formation and repair of connective tissue.

Vitamin E – di-Alpha Tocopherol (35 iu or 100% RDI)
This powerful antioxidant helps improve circulation and is necessary for tissue repair. It is also helpful for normal blood clotting, healing and prevents scarring. It provides athletic support by relaxing cramps and maintains healthy nerves and muscles, while strengthening capillary walls. The alpha form of vitamin E has been found to be the most potent form.

Sources
Trentham, et al., “Effects of Oral Administration of Type II collagen on Rheumatoid Arthritis”, Science, 261:1727-1730, 1993
Trentham, et al., “Effects of Oral Administration of type-II collagen on Rheumatoid Arthritis”, Science, 261:1720-1730, 1993
Barnett, et al., “A Pilot trial of Oral Type II Collagen in the Treatment of Juvenile Rheumatoid Arthritis”, Arthritis & Rheumatism, 39:623-628, 1996
Barnett, et al., “Treatment of Rheumatoid Arthritis with Oral Type II collagen. Results of Multicenter, Double-Blind, Placebo-Controlled Trial”, Arthritis & Rheumatism, 41:290-297, 1998
Sieper, et al., “Oral Type II Collagen Treatment in Early rheumatoid Arthritis. A Double-Blind, Placebo-Controlled, Randomized Trial”, Arthritis & Rheumatism, 39:41-50, 1996
Gimsa, et al., “Type II collagen Serology: A Guide to Clinical Responsiveness to Oral Tolerance?”, Rheumatology International, 16:237-240, 1997
Efficacy of methylsulfonylmethane (MSM) in osteoarthritis pain of the knee: a pilot clinical trial.
Kim LS, Axelrod LJ, Howard P, Buratovich N, Waters RF.
Osteoarthritis Cartilage. 2006 Mar;14(3):286-94. Epub 2005 Nov 23.
Kim LS, Axelrod LJ, Howard P, Buratovich N, Waters RF. 2006. Efficacy of methylsulfonylmethane (MSM) in osteoarthritis pain of the knee: a pilot clinical trial. Osteoarthritis Cartilage 14:286-294.

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.